Lead Drug Discover Strategies from Natural Medicines Based on Network Pharmacology

The need for therapeutics to overcome development of existing diseases research discover new lead agents. In the face public health challenges worldwide, natural medicines play a pivotal role in innovative drug discovery. Network pharmacology can easily construct complicated poly-pharmacology network based on compound, biological function, and bioactive target proteins, which meets overall feature medicines, enable elucidate action mechanism at molecule-protein level with systematic view. this work, we first summarized recent progress delineating its interaction medicines. Second, focused relationship between pharmacology. Additionally, discussed current issues potential prospects from by Further investigations should be focus relevant structural analysis experiment, also dynamic quantitative development. summary, it is rational approach discovery, structure biology research, makes very powerful method molecules high-throughput manner comprehensive special multi-compound protein/disease poly network.